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hydrochlorothiazide sulfa allergy, check these out | Is Hydrochlorothiazide a sulfa drug?

By Jessica Wood

Is Hydrochlorothiazide a sulfa drug?

Hydrochlorothiazide (HCTZ) is a sulfonamide-containing drug with commonly reported adverse effects that include electrolyte abnormalities, orthostatic hypotension, hyperglycemia, and photosensitivity.

Can I take hydrochlorothiazide if allergic to sulfa?

Yep, these are safe if you have a sulfa allergy. Thiazide diuretics like chlorthalidone and hydrochlorothiazide (HCTZ) are used to treat high blood pressure and are fine to take even if you’ve been told you have a sulfa allergy to Bactrim.

What diuretics are safe with sulfa allergy?

Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa.

Why are thiazides contraindicated with sulfa allergy?

Allergists are consulted about the question of hypersensitivity to loop or thiazide diuretics in patients with a history of sulfonamide allergy because it is thought that there is a risk of cross-reactivity from common sulfonamide constituents of these compounds.

Can you be allergic to hydrochlorothiazide?

Allergy warning

Hydrochlorothiazide can cause a severe allergic reaction. Symptoms can include: trouble breathing. swelling of your throat or tongue.

What are allergic reactions to hydrochlorothiazide?

What are the possible side effects of hydrochlorothiazide and lisinopril? Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

What drugs should be avoided with sulfa allergy?

Drugs to Avoid With Sulfa Allergies
Sulfamethoxazole / trimethoprim (Bactrim, Sulfatrim), a sulfa combination drug that can be taken in liquid or pill form for many types of infections.Sulfacetamide (BLEPH-10), drops for eye infections.Sulfadiazine silver (Silvadene), a cream to prevent and treat burn infections.

What pregnancy category is hydrochlorothiazide?

Hydrochlorothiazide / methyldopa Pregnancy Warnings

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

What blood pressure medications contain hydrochlorothiazide?

Hydrochlorothiazide
Brand names: HydroDIURIL, Microzide, Esidrix, Oretic. Drug class(es): thiazide diuretics. Brand names: Amturnide. Brand names: Tekturna HCT. Brand names: Moduretic, Moduretic 5-50. Brand names: Tribenzor. Brand names: Exforge HCT. Brand names: Lotensin HCT. Brand names: Ziac.

Can you take acetazolamide If you have a sulfa allergy?

In summary, the risk of reaction to acetazolamide in a patient with sulfonamide allergy is low. However, acetazolamide is listed as possibly cross-reacting with sulfonamide in drug information and the package insert.

Is chlorthalidone sulfa based?

The pharmacist reports that the drug interaction system is flagging the chlorthalidone as a problem due to ED’s allergy to SMX since chlorthalidone also contains a sulfa moiety.

Do all diuretics have sulfa in them?

A look at Table 1 shows that most diuretic agents are sulfonamide derivatives. The only diuretics that are not are the potassium-sparing diuretics (triamterene, spironolactone, and amiloride) and ethacrynic acid.

Does spironolactone have sulfa in it?

Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa.

What is a thiazide diuretic drug?

Thiazide diuretics are an FDA-approved class of drugs that inhibit reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. By doing so, thiazide diuretics promote natriuresis and diuresis.

What drugs are sulfa based?

Common Sulfonamides
Gantrisin (sulfisoxazole)Bactrim or Septra (trimethoprim and sulfamethoxazole)Sulfadiazine.Azulfidine (sulfasalazine)Zonegran (zonisamide)

Who should not take hydrochlorothiazide?

You should not use hydrochlorothiazide if you are unable to urinate. Before using hydrochlorothiazide, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.

Can blood pressure medicine cause allergic reaction?

Also, when you first start a new high blood pressure medicine, be aware of rare allergic reactions. Call 911 right away if you develop hives, wheezing, vomiting, light-headedness, or swelling in your throat or face.

Is there an alternative to hydrochlorothiazide?

If there were alternative diuretics, why prescribe HCTZ? Chlorthalidone is often offered as an alternative to HCTZ, but has limited pharmaceutical formulations.